Kenneth M Williams Selected Research

Oxypurinol (Oxipurinol)

9/2017	Individualising the dose of allopurinol in patients with gout.
12/2015	Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin.
12/2013	An audit of a therapeutic drug monitoring service for allopurinol therapy.
9/2012	The pharmacokinetics of oxypurinol in people with gout.
5/2012	Oxypurinol, allopurinol and allopurinol-1-riboside in plasma following an acute overdose of allopurinol in a patient with advanced chronic kidney disease.
5/2011	Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in patients with gout.
9/2010	Measurement of urinary oxypurinol by high performance liquid chromatography-tandem mass spectrometry.

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Kenneth M Williams Research Topics

Disease

15	Gout 09/2019 - 01/2007
4	Lactic Acidosis 01/2020 - 02/2011
4	Hypersensitivity (Allergy) 04/2017 - 01/2008
3	Type 2 Diabetes Mellitus (MODY) 01/2020 - 02/2011
3	Exanthema (Rash) 12/2015 - 03/2004
2	Hyperuricemia 04/2017 - 08/2012
2	Chronic Renal Insufficiency 11/2014 - 05/2012
2	Body Weight (Weight, Body) 05/2013 - 07/2006
2	Osteoarthritis 09/2011 - 03/2011
1	Liver Diseases (Liver Disease) 01/2020
1	Invasive Fungal Infections 01/2020
1	Hepatic Insufficiency 01/2020
1	Fibrosis (Cirrhosis) 01/2020
1	Myocardial Infarction 12/2019
1	Arthritis (Polyarthritis) 12/2016
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2016
1	Eosinophilia 12/2015
1	Cicatrix (Scar) 12/2015
1	Renal Insufficiency (Renal Failure) 12/2015
1	Necrosis 12/2015
1	Stevens-Johnson Syndrome (Lyell's Syndrome) 12/2015
1	Gouty Arthritis 10/2015
1	Drug Overdose 11/2014
1	Chronic Disease (Chronic Diseases) 10/2013
1	Hypertension (High Blood Pressure) 10/2013
1	Acute Disease 09/2013
1	Nausea 09/2013
1	Hypoxia (Hypoxemia) 09/2013
1	Acute Kidney Injury (Acute Renal Failure) 09/2013
1	Vomiting 09/2013
1	Mycoses (Diseases, Fungus) 02/2013
1	Pericarditis 01/2009
1	Rheumatoid Arthritis 03/2007
1	Serum Sickness 03/2004
1	Blister (Bulla) 11/2003

Drug/Important Bio-Agent (IBA)

13	Allopurinol (Remid)FDA LinkGeneric 09/2017 - 01/2007
9	Uric Acid (Urate)IBA 09/2019 - 01/2007
7	Oxypurinol (Oxipurinol)IBA 09/2017 - 09/2010
5	Metformin (Glucophage)FDA LinkGeneric 01/2020 - 02/2011
4	Pharmaceutical PreparationsIBA 12/2015 - 01/2007
3	Febuxostat FDA Link 09/2019 - 12/2016
2	Xanthine DehydrogenaseIBA 01/2017 - 12/2016
2	Proteins (Proteins, Gene)FDA Link 12/2015 - 10/2015
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 09/2011 - 03/2011
2	Probenecid (Benemid)FDA LinkGeneric 05/2011 - 01/2008
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2020
1	HLA-B Antigens (HLA-B)IBA 12/2015
1	Toll-Like Receptors (Toll-Like Receptor)IBA 10/2015
1	NLR ProteinsIBA 10/2015
1	InflammasomesIBA 10/2015
1	PyrinIBA 10/2015
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 11/2014
1	DiureticsIBA 10/2013
1	Antihypertensive Agents (Antihypertensives)IBA 10/2013
1	CreatinineIBA 05/2013
1	Itraconazole (Sporanox)FDA LinkGeneric 02/2013
1	Acetaminophen (Paracetamol)FDA LinkGeneric 09/2011
1	Analgesics (Analgesic Drugs)IBA 09/2011
1	BiguanidesIBA 02/2011
1	BenzbromaroneIBA 01/2008
1	Biological ProductsIBA 03/2007
1	Rifampin (Rifampicin)FDA LinkGeneric 07/2006
1	Bupropion (Wellbutrin)FDA LinkGeneric 07/2006
1	hydroxybupropionIBA 07/2006
1	Cytochrome P-450 CYP2B6 (CYP2B6)IBA 07/2006
1	histidine-rich proteinsIBA 03/2004
1	Fluconazole (Zonal)FDA LinkGeneric 11/2003

Therapy/Procedure

7	Therapeutics 01/2020 - 01/2008
1	Chemoprevention 10/2013
1	Organ Transplantation 02/2013
1	Aftercare (After-Treatment) 07/2006